Improved ventilatory response at peak exercise despite no change in peak oxygen consumption with chronic beta-blockade in heart failure patients
نویسندگان
چکیده
منابع مشابه
Skeletal muscle mass independently predicts peak oxygen consumption and ventilatory response during exercise in noncachectic patients with chronic heart failure.
OBJECTIVES We sought to assess whether skeletal muscle mass might be a predictor of peak oxygen consumption (Vo2) and relation of the ventilation to carbon dioxide production (VE/VCo2) slope in patients with chronic heart failure (CHF) independent of clinical conditions, neurohormonal activation and resting hemodynamics. BACKGROUND A variety of abnormalities characterize skeletal muscle and c...
متن کاملCombining peak oxygen consumption and ventilatory efficiency in the prognostic assessment of patients with heart failure.
Exercise ventilatory efficiency (VE/VCO2 slope) and peak oxygen consumption (VO2) are strong mortality predictors in patients with heart failure and we combined these 2 variables' beta coefficients from Cox regression to investigate a new prognostic index. Average follow-up was 3.8+/-1.8 years for 355 patients (72% male, 51+/-10 years). The beta coefficients from peak VO2 (17.3+/-5.0 ml x kg(-1...
متن کاملVentilatory and heart rate responses to exercise: better predictors of heart failure mortality than peak exercise oxygen consumption.
Better Predictors of Heart Failure Mortality Than Peak Exercise Oxygen Consumption To the Editor: We read with great interest the article by Robbins et al1 describing how exercise-related ventilatory and heart rate responses better predict heart failure mortality than peak exercise oxygen consumption.2 Although Robbins et al1 correctly state that other investigators have shown that exercise-rel...
متن کاملLean tissue adjusted peak oxygen consumption in congestive heart failure.
We disagree with the comments made by Dr. F. James Brennan that major events were underreported in our recent Journal article (1). Although we used a composite end point that included death, myocardial infarction, cerebrovascular accident and myocardial revascularization, we also separately reported mortality, myocardial infarction, repeat revascularization procedures and stroke (1). For exampl...
متن کاملVentilatory and heart rate responses to exercise : better predictors of heart failure mortality than peak oxygen consumption.
BACKGROUND An abnormally low chronotropic response and an abnormally high ventilatory response (V(E)/V(CO2)) to exercise are common in patients with severe heart failure, but their relative prognostic impacts have not been well explored. METHODS AND RESULTS Consecutive patients with heart failure referred for metabolic stress testing who were not taking beta-blockers or intravenous inotropes ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2002
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(02)80810-5